Core Pharmacogenomics (Drug-Metabolism) Panel
A core set of pharmacogenes that influence how common medications are metabolized and dosed, drawn from CPIC/PharmGKB-style clinical pharmacogenomic panels.
10 genes · 9 variants
cytochrome P450 family 2 subfamily C member 19
CYP2C19 is a human protein-coding gene.
cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)
CYP2D6 is a human protein-coding gene.
cytochrome P450 family 2 subfamily C member 9
CYP2C9 is a human protein-coding gene.
vitamin K epoxide reductase complex subunit 1
VKORC1 is a human protein-coding gene.
thiopurine S-methyltransferase
TPMT is a human protein-coding gene.
dihydropyrimidine dehydrogenase
DPYD is a human protein-coding gene.
solute carrier organic anion transporter family member 1B1
SLCO1B1 is a human protein-coding gene.
nudix hydrolase 15
NUDT15 is a human protein-coding gene.
UDP glucuronosyltransferase family 1 member A1
UGT1A1 is a human protein-coding gene.
glucose-6-phosphate dehydrogenase
G6PD is a human protein-coding gene.
CYP2C19
rs4244285 is a genetic variant located in the CYP2C19 gene.
CYP2D6
rs3892097 is a genetic variant located in the CYP2D6 gene.
CYP2C9 · p.Ile359Leu
rs1057910 is a genetic variant located in the CYP2C9 gene.
VKORC1
rs9923231 is a genetic variant located in the VKORC1 gene.
TPMT · p.Tyr240Cys
rs1142345 is a genetic variant located in the TPMT gene.
DPYD
rs3918290 is a genetic variant located in the DPYD gene.
SLCO1B1 · p.Val174Ala
rs4149056 is a genetic variant located in the SLCO1B1 gene.
NUDT15 · p.Arg139Cys
rs116855232 is a genetic variant located in the NUDT15 gene.
G6PD · p.Val98Met
rs1050828 is a genetic variant located in the G6PD gene.
Educational information only — not medical advice, a diagnosis, or a clinical recommendation. This panel is a curated grouping of public-record gene and variant pages for reference; it does not reflect your own genome or personal risk. Consult a qualified genetics professional or genetic counselor for interpretation relevant to you.