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rs1057910

CYP2C9*3

CYP2C9missense variantp.Ile359Leusingle nucleotide variant
ClinVar by condition
  • Flurbiprofen responseDrug response · ★ · germline
  • Lesinurad responseDrug response · ★ · germline
  • Piroxicam responseDrug response · ★ · germline
  • Phenytoin responseDrug response · germline
  • Glipizide responseDrug response · germline
  • Warfarin responseDrug response · germline
  • Tolbutamide responseDrug response · germline
  • not providedother · ★ · germline

gnomAD allele frequency 4.90e-2

rs1057910 is a genetic variant located in the CYP2C9 gene. dbsnp · gene

In gnomAD, rs1057910 has an overall allele frequency of 4.9%. gnomad · frequency

In ClinVar, rs1057910 is classified as Drug response for Flurbiprofen response (1 review star, germline; last evaluated 2019-02-11). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Lesinurad response (1 review star, germline; last evaluated 2019-02-11). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Piroxicam response (1 review star, germline; last evaluated 2019-02-11). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Phenytoin response (0 review stars, germline; last evaluated 2020-09-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Glipizide response (0 review stars, germline; last evaluated 2012-06-15). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Warfarin response (0 review stars, germline; last evaluated 2012-06-15). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as Drug response for Tolbutamide response (0 review stars, germline; last evaluated 2010-12-30). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1057910 is classified as other for not provided (1 review star, germline; last evaluated 2015-07-10). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

Sources

retrieved 2026-08-03 · facts 616703cdae9ac7bc · meta/llama-3.1-8b-instruct · prompt 4.0.1 · schema 3.0.0

Educational information only — not medical advice, a diagnosis, or a clinical interpretation. A variant's significance can be uncertain, conflicting, or dependent on your full clinical and family context. Consult a qualified genetics professional or genetic counselor before drawing any conclusion.