rs9923231
NM_024006.4(VKORC1):c.-1639G>A
- warfarin response - DosageDrug response · ★★★ · germline
- phenprocoumon response - DosageDrug response · ★★★ · germline
- phenprocoumon response - ToxicityDrug response · ★★★ · germline
- warfarin response - ToxicityDrug response · ★★★ · germline
- acenocoumarol response - DosageDrug response · ★★★ · germline
- warfarin response - EfficacyDrug response · ★★★ · germline
- Warfarin responsePathogenic · germline
- Venous thromboembolismProtective · biparental
- ThrombusUncertain significance · germline
- VKORC1-related disorderLikely benign · germline
- not providedBenign · ★★ · germline
- not specifiedLikely benign · ★ · germline
gnomAD allele frequency 3.26e-1
rs9923231 is a genetic variant located in the VKORC1 gene. dbsnp · gene
In gnomAD, rs9923231 has an overall allele frequency of 32.6%. gnomad · frequency
In ClinVar, rs9923231 is classified as Drug response (dosage) for warfarin response (3 review stars, germline; last evaluated 2021-11-19). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Drug response (dosage) for phenprocoumon response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Drug response (toxicity) for phenprocoumon response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Drug response (toxicity) for warfarin response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Drug response (dosage) for acenocoumarol response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Drug response (efficacy) for warfarin response (3 review stars, germline; last evaluated 2021-03-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Pathogenic for Warfarin response (0 review stars, germline; last evaluated 2010-09-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Protective for Venous thromboembolism (0 review stars, biparental). clinvar · classificationclinvar · review confidenceclinvar · origin
In ClinVar, rs9923231 is classified as Uncertain significance for Thrombus (0 review stars, germline). clinvar · classificationclinvar · review confidenceclinvar · origin
In ClinVar, rs9923231 is classified as Likely benign for VKORC1-related disorder (0 review stars, germline; last evaluated 2021-07-20). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Benign for not provided (2 review stars, germline; last evaluated 2024-03-25). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Likely benign for not specified (1 review star, germline; last evaluated 2018-03-09). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs9923231 is classified as Uncertain significance for See cases (0 review stars, germline). clinvar · classificationclinvar · review confidenceclinvar · origin
retrieved 2026-08-03 · facts ad13dffbb7270b3d · meta/llama-3.1-8b-instruct · prompt 4.0.1 · schema 3.0.0
Educational information only — not medical advice, a diagnosis, or a clinical interpretation. A variant's significance can be uncertain, conflicting, or dependent on your full clinical and family context. Consult a qualified genetics professional or genetic counselor before drawing any conclusion.