rs80359550

rs80359550 is a genetic variant located in the BRCA2 gene. dbsnp · gene

In gnomAD, rs80359550 has an overall allele frequency of 0.02%. gnomad · frequency

In ClinVar, rs80359550 is classified as Pathogenic for BRCA2-related cancer predisposition (3 review stars, germline; last evaluated 2024-06-11). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Hereditary cancer-predisposing syndrome (2 review stars, germline; last evaluated 2025-02-24). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Hereditary breast ovarian cancer syndrome (2 review stars, germline; last evaluated 2025-02-03). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Breast-ovarian cancer, familial, susceptibility to, 2 (BROVCA2) (2 review stars, germline; last evaluated 2024-07-04). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Familial cancer of breast (2 review stars, germline; last evaluated 2024-05-06). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Fanconi anemia complementation group D1 (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Medulloblastoma (MDB) (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Wilms tumor 1 (WT1) (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Pancreatic cancer, susceptibility to, 2 (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Glioma susceptibility 3 (GLM3) (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Familial prostate cancer (1 review star, germline; last evaluated 2024-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Breast and/or ovarian cancer (1 review star, germline; last evaluated 2022-03-06). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for BRCA2-related disorder (1 review star, germline; last evaluated 2017-04-28). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Breast neoplasm (1 review star, germline). clinvar · classificationclinvar · review confidenceclinvar · origin

In ClinVar, rs80359550 is classified as Pathogenic for Endometrial carcinoma (0 review stars, germline; last evaluated 2023-02-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Ovarian neoplasm (0 review stars, germline; last evaluated 2018-12-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs80359550 is classified as Pathogenic for Fanconi anemia complementation group D1 (0 review stars; last evaluated 2016-09-12). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs80359550 is classified as Risk factor for Pancreatic cancer, susceptibility to, 2 (0 review stars; last evaluated 2016-09-12). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs80359550 is classified as not provided for Fanconi anemia complementation group D1 (0 review stars). clinvar · classificationclinvar · review confidence

In ClinVar, rs80359550 is classified as not provided for Hereditary breast ovarian cancer syndrome (0 review stars). clinvar · classificationclinvar · review confidence

In ClinVar, rs80359550 is classified as Pathogenic for not provided (2 review stars, germline; last evaluated 2025-03-04). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date