rs429358

rs429358 is a genetic variant located in the APOE gene. dbsnp · gene

In gnomAD, rs429358 has an overall allele frequency of 16.4%. gnomad · frequency

In ClinVar, rs429358 is classified as Pathogenic for Alzheimer disease 4 (AD4) (1 review star; last evaluated 2020-03-24). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs429358 is classified as Likely pathogenic for Alzheimer disease (1 review star, germline; last evaluated 2019-06-27). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Risk factor for Primary degenerative dementia of the Alzheimer type, presenile onset (1 review star, germline; last evaluated 2019-01-16). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Uncertain significance for Lipoprotein glomerulopathy (LPG) (1 review star; last evaluated 2019-01-01). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs429358 is classified as Pathogenic (risk factor) for Alzheimer disease 2 (AD2) (0 review stars, germline; last evaluated 2022-06-27). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Pathogenic for APOE4(-)-FREIBURG (0 review stars, germline; last evaluated 2017-02-15). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Pathogenic for Familial type 3 hyperlipoproteinemia (0 review stars, germline; last evaluated 1993-05-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Likely pathogenic for Familial hypercholesterolemia (0 review stars, germline; last evaluated 2020-05-27). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Drug response for Warfarin response (0 review stars; last evaluated 2010-08-31). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs429358 is classified as not provided for Familial type 3 hyperlipoproteinemia (0 review stars, germline; last evaluated 2023-06-08). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as association for APOE5 VARIANT (0 review stars, germline; last evaluated 2019-11-22). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Conflicting interpretations (risk factor) for not provided (1 review star, germline; last evaluated 2024-10-15). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs429358 is classified as Uncertain significance for not specified (1 review star, germline; last evaluated 2019-01-18). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date