rs361525
NC_000006.12:g.31575324G>A
- Susceptibility to severe coronavirus disease (COVID-19) due to high plasma levels of TNF, TNFR, and/or TNFR5Uncertain significance · germline
- Susceptibility to severe coronavirus disease (COVID-19)Uncertain significance · germline
gnomAD allele frequency 3.87e-2
rs361525 is a genetic variant located in the TNF gene. dbsnp · gene
In gnomAD, rs361525 has an overall allele frequency of 3.9%. gnomad · frequency
In ClinVar, rs361525 is classified as Uncertain significance for Susceptibility to severe coronavirus disease (COVID-19) due to high plasma levels of TNF, TNFR, and/or TNFR5 (0 review stars, germline; last evaluated 2021-08-07). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
In ClinVar, rs361525 is classified as Uncertain significance for Susceptibility to severe coronavirus disease (COVID-19) (0 review stars, germline; last evaluated 2021-02-09). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date
retrieved 2026-08-03 · facts bfbbb0d98697c6f2 · meta/llama-3.1-8b-instruct · prompt 4.0.1 · schema 3.0.0
Educational information only — not medical advice, a diagnosis, or a clinical interpretation. A variant's significance can be uncertain, conflicting, or dependent on your full clinical and family context. Consult a qualified genetics professional or genetic counselor before drawing any conclusion.