rs28934574

rs28934574 is a genetic variant located in the TP53 gene. dbsnp · gene

In ClinVar, rs28934574 is classified as Pathogenic for Li-Fraumeni syndrome (LFS) (2 review stars; last evaluated 2025-02-03). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs28934574 is classified as Likely pathogenic for Hereditary cancer-predisposing syndrome (2 review stars, germline; last evaluated 2024-07-05). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Likely pathogenic for Li-Fraumeni syndrome 1 (LFS) (2 review stars, germline; last evaluated 2023-07-07). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for Adrenocortical carcinoma, hereditary (ADCC) (1 review star; last evaluated 2024-02-14). clinvar · classificationclinvar · review confidenceclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for Astrocytoma, anaplastic (1 review star, germline; last evaluated 2016-11-04). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for Pleomorphic xanthoastrocytoma (PXA) (1 review star, germline; last evaluated 2016-11-04). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for Squamous cell carcinoma of the head and neck (HNSCC) (1 review star, somatic). clinvar · classificationclinvar · review confidenceclinvar · origin

In ClinVar, rs28934574 is classified as Pathogenic for Colorectal cancer (1 review star, somatic). clinvar · classificationclinvar · review confidenceclinvar · origin

In ClinVar, rs28934574 is classified as Likely pathogenic for Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype (1 review star, germline; last evaluated 2019-02-12). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for TP53-related disorder (0 review stars, germline; last evaluated 2024-10-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for Li-fraumeni-like syndrome (0 review stars, germline; last evaluated 1995-01-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Likely pathogenic for Ovarian neoplasm (0 review stars, somatic; last evaluated 2018-12-01). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs28934574 is classified as Pathogenic for not provided (2 review stars, germline; last evaluated 2021-05-21). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date