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rs1138272

NM_000852.4(GSTP1):c.341C>T (p.Ala114Val)

GSTP1missense variantp.Ala114Valsingle nucleotide variant
ClinVar by condition
  • GLUTATHIONE S-TRANSFERASE PI POLYMORPHISM, TYPE CBenign · germline
  • Pulmonary disease, chronic obstructive, susceptibility toassociation · germline
  • not providedBenign · ★★ · germline

gnomAD allele frequency 6.09e-2

rs1138272 is a genetic variant located in the GSTP1 gene. dbsnp · gene

In gnomAD, rs1138272 has an overall allele frequency of 6.1%. gnomad · frequency

In ClinVar, rs1138272 is classified as Benign for GLUTATHIONE S-TRANSFERASE PI POLYMORPHISM, TYPE C (0 review stars, germline; last evaluated 1997-04-11). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1138272 is classified as association for Pulmonary disease, chronic obstructive, susceptibility to (0 review stars, germline; last evaluated 2022-07-05). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

In ClinVar, rs1138272 is classified as Benign for not provided (2 review stars, germline; last evaluated 2021-06-09). clinvar · classificationclinvar · review confidenceclinvar · originclinvar · assertion date

Sources

retrieved 2026-08-03 · facts 7b737a1be3197858 · meta/llama-3.1-8b-instruct · prompt 4.0.1 · schema 3.0.0

Educational information only — not medical advice, a diagnosis, or a clinical interpretation. A variant's significance can be uncertain, conflicting, or dependent on your full clinical and family context. Consult a qualified genetics professional or genetic counselor before drawing any conclusion.