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Familial Hypercholesterolemia Panel

The three genes most commonly implicated in familial hypercholesterolemia, an inherited cause of very high LDL cholesterol and early cardiovascular disease.

3 genes · 2 variants

LDLRgene

low density lipoprotein receptor

LDLR is a human protein-coding gene.

APOBgene

apolipoprotein B

APOB is a human protein-coding gene.

PCSK9gene

proprotein convertase subtilisin/kexin type 9

PCSK9 is a human protein-coding gene.

rs121908025variant

LDLR · p.Trp87Gly

rs121908025 is a genetic variant located in the LDLR gene.

rs11591147variant

PCSK9 · p.Arg46Leu

rs11591147 is a genetic variant located in the PCSK9 gene.

Educational information only — not medical advice, a diagnosis, or a clinical recommendation. This panel is a curated grouping of public-record gene and variant pages for reference; it does not reflect your own genome or personal risk. Consult a qualified genetics professional or genetic counselor for interpretation relevant to you.